Determined to keep Annabelle from further destruction and chaos, demonologists ed and Lorraine Warren bring the possessed doll to a locked artifact room in their home, placing it under "secure" sanctified glass and enlisting the blessing of a priest. However, a hopeless night of horror awaits the inhabitants of the house, when Annabelle awakens the evil spirits of the room and their new target is the ten-year-old daughter of Warren Judy and her friends.